Radioiodine therapy of funcitonal autonomy using the functional autonomous volume
Seeger, T.; Emrich, D.; Sandrock, D.
NUKLEARMEDIZIN. Nuclear Medicine 34(4): 135-140
1995
ISSN/ISBN: 0029-5566 PMID: 7675642 Document Number: 443307
In order to determine the effective radiation dose to be delivered by 131I in functional autonomy we have used the functional autonomous volume calculated from the global 99mTc thyroid uptake under exogenous or endogenous suppression before and 3 to 7 months after treatment. The radiation dose to the autonomous volume was calculated retrospectively in 131 patients with unifocal, multifocal and disseminated autonomy (75 hyperthyroid, 56 euthyroid) who received 131I treatment of 200-300 Gy to the total volume of the gland. It could be shown that at least 350 Gy to the autonomous volume are required to reach the desired effect of treatment which was dependent only on the radiation dose delivered to the functional autonomous volume.