False high levels glycosylated hemoglobin in 2 diabetic patients with persistence of fetal hemoglobin
Villanueva, C.L.; Zavala, C.; Alcayaga, M.P.
Revista Medica de Chile 123(9): 1129-1132
1995
ISSN/ISBN: 0034-9887 PMID: 8728737 Document Number: 442236
Two diabetic patients with unusual high levels of glycosylated hemoglobin measured by ion exchange chromatography are described. Further studies revealed a persistence of fetal hemoglobin in both cases. This condition produces falsely high levels of glycosylated hemoglobin, when ion exchange chromatography is used. These cases may be overtreated with risk of hypoglycemia. Patients with inappropriate levels of glycosylated hemoglobin should be investigated for hemoglobinopathies.