Pancreatic malignant neoplasms at the Instituto Nacional de la Nutrición
Córdova, J.A.; de Jesús Villalobos, J.; Campuzano, M.; López, G.
Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 31(2): 121-126
1979
ISSN/ISBN: 0034-8376 PMID: 472541 Document Number: 4417
We reviewed 139 cases of pancreatic cancer, pathologically confirmed, ocurring between 1945-1977 in the Instituto Nacional de la Nutrición. This neoplasm ranked in 4th place in the list of all gastrointstinal cancer in the Institute. 60 per cent of the patients were men. 80 per cent were between the fourth and sixth decade of life. The most frequent symptoms were: weight loss (96%), malaise (90%), pain (76%) and jaundice (48%). In 55 per cent the tumor was located in the head of the pancreas. Radiographic procedures, such as upper G-I studies and coeliac trunk arteriography afforded the most important diagnostic information. This review ended in 1977. Since this is a retrospective study the efficacy of new diagnostic procedures such as ultrasonography and computed tomography were not evaluated. These new techniques are probably the best procedures for the early detection of pancreatic tumors. Pathologically 73 per cent of the tumors were found to be adenocarcinomas and 11.5 had malignant islet cells. Paliative treatment was utilized in 68.4 per cent of the patients, while in 10 per cent extensive curative surgical procedures were performed. The overall mean survival rete was 5.4 months. Only two patients survived more than five years.
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