Clinical significance of c-myc gene in esophageal squamous cell carcinoma

He, J.; Zhang, R.G.; Zhu, D.

Zhonghua Yi Xue Za Zhi 75(2): 94

1995


ISSN/ISBN: 0376-2491
PMID: 7767777
Document Number: 441691
Using polymerase chain reaction, we analysed 41 samples of esophageal squamous cell cancer at molecular level. Amplification of c-myc gene was found in 16 (39%). C-myc gene amplification was found to be related to lymph node metastasis, TNM staging (P < 0.01) and also prognosis (P < 0.05). We thought that c-myc gene was the prognosis factor for the patients with esophageal squamous cell carcinoma.

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