Solid-cystic tumor of the pancreas. An extensive ultrastructural study of fourteen cases
Balercia, G.; Zamboni, G.; Bogina, G.; Mariuzzi, G.M.
Journal of Submicroscopic Cytology and Pathology 27(3): 331-340
1995
ISSN/ISBN: 1122-9497 PMID: 7671214 Document Number: 441072
Fourteen cases of solid-cystic tumor of the pancreas have been investigated at the ultrastructural level. A heterogeneous cell population has been found, and some distinctive features have been identified: oncocytoid cells; clear cells reminiscent of ductular and centro-acinar cells; cells with exocrine and endocrine features; cells with bundles of microfilaments and dense bodies, reminiscent of myoepithelium. This varied differentiation strongly suggests the tumor histogenesis to be from a multipotent cell capable of recapitulating the normal ontogenesis during its neoplastic proliferation. Furthermore, the heterogeneity in ultrastructural appearance is a characteristic and reliable feature of sold-cystic tumor of the pancreas.