Study on decision support system for the interpretation of laboratory data by an artificial neural network--with a special reference to estimation for histological diagnosis of liver diseases with laboratory data on liver function
Okamoto, Y.; Nakano, H.; Yoshikawa, M.; Matsuoka, H.; Sakamoto, T.; Tsujii, T.
Rinsho Byori. Japanese Journal of Clinical Pathology 42(2): 195-199
1994
ISSN/ISBN: 0047-1860 PMID: 8139129 Document Number: 436660
An artificial neural network (ANN) was trained on laboratory data of liver function tests to estimate for histological diagnosis in patients with liver diseases such as chronic hepatitis, liver cirrhosis and fatty liver. ANN diagnosed accurately 95.3% of the cases for training and 50% of the test cases. Elimination of ZTT, GOT or A/G ratio from the data set for input reduced the ability of accurate diagnosis, whereas elimination of TBA raised this ability to 66.7%. On the other hand, accuracy of physician in diagnosing the test cases ranged from 20.8 to 62.5%. From our results it is expected that ANN may support a physician's decision on the interpretation of laboratory data.