The ultrastructure of the capillaries and pericapillary area in the formations of the rat forebrain in hypokinesia
Zhvaniia, M.G.; Kakabadze, I.M.
Morfologiia 107(7-12): 47-53
1994
ISSN/ISBN: 1026-3543 PMID: 8680572 Document Number: 436281
Capillaries and pericapillary tissue were studied in central and lateral nuclei of amygdala, cingulate cortex, hippocampal fields CA1 and CA3 and sensomotor, cortex in rats, exposed to hypokinesia 40, 90 and 120 days lasted. Changes, growing more numerous and variable in proportion with the time of hypokinesia were found. The most essential changes were hypertrophy of glial elements with either decreased or increased functional activity. Alteration of the endotheliocyte structure, pinocytosis, hypertrophy and increase of nuclear and cytoplasmic osmophilia, decrease of the folding were noted. Capillaries with significantly increased folding and narrow or containing unidentified substance lumen were encountered in 120-days hypokinesia. In limbic structures pericapillary glia is represented mostly with astrocytes, in neocortex-also with oligodendrocytes.