Experimental validation of the efficacy of intraocular phonoelectrophoresis in eye diseases
Egorov, E.A.; Kriukova, M.B.; Kriukov, A.I.
Vestnik Oftalmologii 110(1): 20-23
1994
ISSN/ISBN: 0042-465X PMID: 8191656 Document Number: 435618
Basing on clinical data (12 patients) and experimental results (42 rabbits), the authors defined the pharmacokinetic characteristics of drugs administered by endo-ocular phonoelectrophoresis technique developed by them. Formation of the drugs' depot in the parabulbar space was demonstrated. Concentrations of the administered drugs in various segments of the eyeball were assessed. The values obtained during parabulbar injection of drugs were used as reference ones.