Malignant melanoma in epiluminescent microscopy
Schulz, H.
Der Hautarzt; Zeitschrift für Dermatologie Venerologie und verwandte Gebiete 45(1): 15-19
1994
ISSN/ISBN: 0017-8470 PMID: 8150611 Document Number: 435245
Comparison by skin epiluminescent microscopy of 60 malignant melanomas and 130 junctional and compound naevocellular naevi revealed statistically significant differences for 12 characteristics. The following microscopical in vivo signs that can be defined by histopathological examination were found only in malignant or premalignant melanocytic lesions: digitated radial streaming, grevish-blue reticular patterns, opaque gypseous alabaster lacunas, brown/black dots on a blue/greyish background, pseudopodia at the periphery and blue-in-pink areas. Nevertheless, specific epiluminescent phenomena of histopathologically defined malignant melanomas are still unknown. Therefore, diagnostic evaluation of malignancy is based mainly on microscopic assessment of combined details of morphology and colour of melanocytic tumours.