Acute renal failure associated with minimal change nephrotic syndrome in an elderly adult
Morita, A.; Ishimura, E.; Tabata, T.; Shoji, S.; Inoue, T.; Nishizawa, Y.; Morii, H.
Osaka City Medical Journal 40(1): 37-42
1994
ISSN/ISBN: 0030-6096 PMID: 9309942 Document Number: 435082
We report a 66-year-old man with minimal change nephrotic syndrome (MCNS) that was associated with reversible acute renal failure (ARF) caused by acute tubular necrosis (ATN). He had a subacute onset of proteinuria and progressive azotemia. Hemodialysis (HD) was required to improved azotemia. Renal biopsy revealed minor glomerular abnormalities associated with ATN. While continuing HD, steroid therapy was started, which subsequently allowed the patient to be weaned from HD and relieved from NS. In this patient, histological examination and clinical course suggested that ATN was probably induced by hypovolemia due to MCNS.