Models of the organization of neonatal screening
Cassio, A.; Piazzi, S.; Colli, C.; Balsamo, A.; Bozza, D.; Salardi, S.; Sprovieri, G.; Cacciari, E.
Annali Dell'istituto Superiore di Sanita 30(3): 269-273
1994
ISSN/ISBN: 0021-2571 PMID: 7879991 Document Number: 434858
The authors evaluate the different organizational strategies of a congenital hypothyroidism screening program. Positive and negative aspects of laboratory screening tests (TSH only, T4-supplemental TSH, TSH and T4), organization strategies (centralization or decentralization), recall and first follow-up criteria are examined. The authors consider that the necessity for an early diagnostic confirmation can be associated with a precise etiologic diagnosis and an evaluation of the prenatal severity of congenital hypothyroidism factors. Some European and North-American experiences are compared with the activity of a regional Italian screening center.