Comparison of Nd-Yag laser and strip biopsy in the treatment of extensive adenomas of the rectum
De Palma, G.D.; Sivero, L.; Caiazzo, C.; Di Matteo, E.; Triscino, G.G.; Catanzano, C.
Minerva Chirurgica 49(4): 259-264
1994
ISSN/ISBN: 0026-4733 PMID: 8072699 Document Number: 434647
This prospective study was carried out in order to compare endoscopic laser therapy and strip biopsy for treatment of large sessile rectal adenomas. Between January 1990 and December 1991, 94 consecutive patients, referred to our Endoscopy Service because of extensive rectal adenoma have been allocated to laser therapy or strip biopsy. The effectiveness of the two techniques was statistically the same from many points of view: complete ablation (76.7% vs 71.4%), recurrence (35.4% vs 30.6%) need for surgical intervention (12% vs 16.6%) and complication rates. However, from our experience, the treatment period was significantly shorter for patients affected by an intermediate sized adenoma and treated with strip biopsy. In both groups, instead, complete, permanent ablation was difficult to obtain in the cases of extensive lesions and in particular if they were localized lower than 5 cm from the anus.