Sulfasalazine induced seizures and dysphasia
Hill, M.E.; Gordon, C.; Situnayake, R.D.; Heath, D.A.
Journal of Rheumatology 21(4): 748-749
1994
ISSN/ISBN: 0315-162X PMID: 7913503 Document Number: 434038
We describe the case of a 46-year-old woman with rheumatoid arthritis who developed a severe reaction to sulfasalazine, characterized by dysphasia, seizures, rash and the development of strongly positive pANCA (perinuclear antineutrophil cytoplasmic antibodies). Her condition improved spontaneously upon withdrawal of sulfasalazine. Dysphasia has not been reported as a side effect of sulfasalazine.