Carcinoma of the external auditory meatus and middle ear. Results of the treatment of 28 cases
Gabriele, P.; Magnano, M.; Albera, R.; Canale, G.; Redda, M.G.; Krengli, M.; Negri, G.L.
Tumori 80(1): 40-43
1994
ISSN/ISBN: 0300-8916 PMID: 8191597 Document Number: 433523
Aims: The authors report their experience on the treatment of 28 cases of middle ear (3) and external auditory meatus (EAM) cancers (25) with surgery and/or radiation therapy. According to histologic type, there were 23 squamous cell carcinomas, 4 basal cell carcinomas and 1 adenocystic carcinoma. Methods: Surgery alone was performed in 2 cases, surgery combined with radiotherapy in 11 cases, and radiotherapy alone in 15 cases. Postoperative radiation therapy dose ranged between 4500 and 5500 cGy; the definitive dose was 6000-7000 cGy. The median follow-up was 61 months. Results: Complete response rate 6 weeks after the end of the treatment, evaluated by CT scan, was 85.7% (24/28). Definitive local control was obtained in 20/28 cases for the primary site and in 26/28 cases for the neck. Nine of the 10 recurrences were retreated with low-dose radiotherapy combined with surgery, chemotherapy or hyperthermia. A new local control was obtained in 2 cases. Four patients were lost during the follow-up at 13, 14,17 and 23 months after the end of the treatment The survival rate was 54% (13/24); disease-free survival was 50% (11/22). Conclusions: Despite a not very aggressive treatment, our results are quite good.