Recent advances in the chemotherapy of AIDS
Verma, S.
Indian Journal of Physiology and Pharmacology 38(1): 5-16
1994
ISSN/ISBN: 0019-5499 PMID: 8132245 Document Number: 431308
Acquired immunodeficiency syndrome (AIDS) continues to grow unabated and in pandemic proportions around the world. The complexity and high mutational ability of the etiologic agent, human immunodeficiency virus, has posed an unprecedented threat toward the chemotherapy of AIDS. Use of contemporary virology to unfold the mystery of HIV-1 and the discovery of key molecular targets for chemotherapeutic intervention has accelerated the quest for safe and effective anti-HIV agents. The vital states in viral replication amenable to inhibition by novel chemical entities and representative examples from diverse chemical classes as potential anti-AIDS agents are presented in this review.