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Accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate therapy

Abu-Shakra, M.; Nicol, P.; Urowitz, M.B.

Journal of Rheumatology 21(5): 934-937

1994

ISSN/ISBN: 0315-162X
PMID: 8064737
Document Number: 430662
We describe a patient with seropositive erosive rheumatoid arthritis (RA) who developed accelerated nodulosis, pleural effusion, and pericardial tamponade during methotrexate (MTX) therapy while her arthritis remained inactive. MTX is an effective therapy for the articular manifestations of RA. However, on occasion it may result in triggering the development of extraarticular manifestations of RA.

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