Nucleozymes and minizymes
Zhenodarova, S.M.
Molekuliarnaia Biologiia 28(3): 506-510
1994
ISSN/ISBN: 0026-8984 PMID: 8052243 Document Number: 428765
The data on the replacement of ribonucleotides within ribozymes with deoxyribonucleotides are reviewed. Resulting chimeric ribozymes ("nucleozymes") are many times more stable than their precursors. Synthesis of minimized ribozymes or minimized nucleozymes ("minizymes") are discussed.