TAME-esterase activity during a prolonged attack of asthma
Subratty, A.H.; Yan, M.Y.; Shun, L.H.; Hebe, A.; Soomaree, V.
International Journal of Clinical Pharmacology and Therapeutics 32(11): 598-599
1994
ISSN/ISBN: 0946-1965 PMID: 7874373 Document Number: 428736
We measured serum N-alpha-tosyl-L-arginine methyl ester (TAME)-esterase activity in a group of patients suffering from a prolonged attack of asthma. Measurements were made pre and post salbutamol nebulization. Our results showed that TAME-esterase activity did not change significantly pre or post nebulization. Based on our experimental data, we concluded that increase serum TAME-esterase activity is a biochemical substance associated with the early asthmatic response but not with prolonged attack of asthma.