The role of inhaled steroids in the treatment of bronchopulmonary dysplasia
Avent, M.L.; Gal, P.; Ransom, J.L.
Neonatal Network Nn 13(3): 63-69
1994
ISSN/ISBN: 0730-0832 PMID: 7512192 Document Number: 428353
Bronchopulmonary dysplasia has been well described in premature infants requiring mechanical ventilation. Systemic steroids are one of many treatment modalities used in the management of these infants, but these agents have been associated with a number of adverse effects. Aerosolized therapy has been proposed as an alternative in order to minimize the systemic complications that occur with the parenteral route. The initial reports of inhaled steroids, although limited, have shown promising results with minimal side effects. This article addresses the mechanism of action, the role in therapy, and potential complications associated with the use of inhaled steroids in the treatment of bronchopulmonary dysplasia.