Hemifacial malignant granuloma as clinical manifestation of peripheral T-cell lymphoma
Fernández-Nogueras Jiménez, F.J.; Fernández Pérez, A.; Moreno León, J.; Fernández-Nogueras Jiménez, V.
Acta Otorrinolaringologica Espanola 45(5): 369-373
1994
ISSN/ISBN: 0001-6519 PMID: 7811513 Document Number: 424545
The present clinical and pathological study describes the cases of two patients having infiltrate and ulcerous lesions of the nose, hard palate and rhinopharynx clinically consistent with a malignant midline granuloma. Histologically, infiltrates presented atypical lymphoid cells around small vessels and damage of the vascular wall. Immunohistologic study, using monoclonal antibodies on both fresh and paraffin embedded tissues, led to the positive diagnosis of peripheral lymphoma of T cells.