Photodynamic therapy for nasal and aural squamous cell carcinoma in cats
Peaston, A.E.; Leach, M.W.; Higgins, R.J.
Journal of the American Veterinary Medical Association 202(8): 1261-1265
1993
ISSN/ISBN: 0003-1488 PMID: 8496082 Document Number: 422460
Eighteen random-bred cats with a total of 19 nasal or dural squamous cell carcinomas were treated with photodynamic therapy, using aluminum phthalocyanine tetrasulfhonate as the photosensitizer. Cats were irradiated at power densities of 100 m W/cm-2 and energy densities of 100 J/cm-2. Successful outcome was obtained in 10 tumors after 1 treatment, and 2 more tumors had complete responses after 1 or 2 additional treatments. Treatments. Treatments were more effective in tumors of stage T-2 or earlier. Five tumors had partial responses, and the response of 2 tumors could not be evaluated. The treatment was safe and well tolerated by most cats, although we found that cats should be kept out of sunlight for 2 weeks after treatment.