Keratinocytes from cell culture for therapy of skin defects. Review and personal results
Schönfeld, M.; Moll, I.; Maier, K.; Jung, E.G.
Der Hautarzt; Zeitschrift für Dermatologie Venerologie und verwandte Gebiete 44(5): 281-289
1993
ISSN/ISBN: 0017-8470 PMID: 8320114 Document Number: 421790
The development of a method to cultivate and expand human keratinocytes in vitro by Rheinwald and Green in the mid-1970s can be considered a milestone in the search for the ideal biological skin substitute. For more than 10 years, cultured keratinocytes have now been used for the treatment of various wounds. In this paper the present status knowledge and the authors own experience after treating 29 patients are discussed.