IgG, modified with coproporphyrin i and the possibility of direct measurement of the antigen-antibody complex

Lepesheva, G.I.; Turko, I.V.; Shestakov, V.L.; Chashchin, V.L.; Lepesheva, G.I; Turko, I.V; Shestakov, V.L; Chashchin, V.L

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IgG, modified with coproporphyrin i and the possibility of direct measurement of the antigen-antibody complex

Lepesheva, G.I.; Turko, I.V.; Shestakov, V.L.; Chashchin, V.L.

Biokhimiia 58(6): 938-943

1993

ISSN/ISBN: 0320-9725

PMID: 8364116

Document Number: 421042

Modification of rabbit IgG by coproporphyrin I activated by Woodward's reagent K as well as antigen-binding and fluorescent properties of coproporphyrin-IgG have been studied. It was shown that coproporphyrin I modified IgG retains its capacity to bind the antigen. The formation of the immune antigen-antibody complex increases the intensity of coproporphyrin-IgG fluorescence.