Ischemic cerebrovascular accidents in homozygous sickle cell anemia. Two case reports
Mbonda, E.; Thuret, I.; Pinsard, N.
Annales de Pediatrie 40(1): 23-27
1993
ISSN/ISBN: 0066-2097 PMID: 8442641 Document Number: 420976
Two cases of ischemic stroke in children of Tunisian descent with sickle cell anemia are reported. Patients were aged 3 years and 14 years, respectively. Periodic partial exchange transfusions with sedimented red blood cells of identical phenotype prevented further episodes of ischemic stroke. Transplantation of HLA-identical bone marrow from a family member offers a chance of complete cure of the hemoglobin disorder in these children who are at risk of recurrent stroke.