The immunopharmacodynamics of mival
Shirinskiĭ, V.S.; Zhuk, E.A.; Baryshok, V.P.
Eksperimental'naia i Klinicheskaia Farmakologiia 56(6): 43-45
1993
ISSN/ISBN: 0869-2092 PMID: 8111299 Document Number: 420630
The authors studied in vitro the immunopharmacodynamics of the new silantrane mival. It was shown that mival possessed mitogenic effects on mononuclear cell proliferation in donors and patients with rheumatoid arthritis. The drug stimulated mononuclear cell proliferation, by acting selectively on T lymphocytes, enhancing T-cell growth lymphokine production, T-suppressor cell activity, and inhibiting prostaglandin E2 production.