Lipoprotein (a) and its role in occlusive vascular disease
Tennant, M.; McGeachie, J.K.
Annals of the Royal College of Surgeons of England 75(1): 3-7
1993
ISSN/ISBN: 0035-8843 PMID: 8422141 Document Number: 420259
An increased serum level of lipoprotein(a) (LP(a)) is acknowledged as an independent risk factor for occlusive vascular disease, especially atherosclerosis. Recently, a considerable amount of data has been produced on the structure and functional relationships between Lp(a) and the primary cellular interactions of atherosclerosis. In this review we discuss the structure and function of Lp(a) with specific reference to its role in the proposed mechanisms of atherosclerosis.