National case-control study of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men: Part 1. Epidemiologic results
Jaffe, H.W.; Choi, K.; Thomas, P.A.; Haverkos, H.W.; Auerbach, D.M.; Guinan, M.E.; Rogers, M.F.; Spira, T.J.; Darrow, W.W.; Kramer, M.A.; Friedman, S.M.; Monroe, J.M.; Friedman-Kien, A.E.; Laubenstein, L.J.; Marmor, M.; Safai, B.; Dritz, S.K.; Crispi, S.J.; Fannin, S.L.; Orkwis, J.P.; Kelter, A.; Rushing, W.R.; Thacker, S.B.; Curran, J.W.
Annals of Internal Medicine 99(2): 145-151
1983
ISSN/ISBN: 0003-4819 PMID: 6603806 DOI: 10.7326/0003-4819-99-2-145Document Number: 419668
To identify risk factors for the occurrence of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men, we conducted a case-control study in New York City, San Francisco, Los Angeles, and Atlanta. Fifty patients (cases) (39 with Kaposi's sarcoma, 8 with pneumocystis pneumonia, and 3 with both) and 120 matched homosexual male controls (from sexually transmitted disease clinics and private medical practices) participated in the study. The variable most strongly associated with illness was a larger number of male sex partners per year (median, 61 for patients; 27 and 25 for clinic and private practice controls, respectively). Compared with controls, cases were also more likely to have been exposed to feces during sex, have had syphilis and non-B hepatitis, have been treated for enteric parasites, and have used various illicit substances. Certain aspects of a lifestyle shared by a subgroup of the male homosexual population are associated with an increased risk of Kaposi's sarcoma and pneumocystis pneumonia.