Infarcted intramural uterine leiomyomata during buserelin acetate treatment
Chang, M.Y.; Tsai, F.B.; Soong, Y.K.
Changgeng Yi Xue Za Zhi 16(2): 129-132
1993
ISSN/ISBN: 2072-0939 PMID: 8339156 Document Number: 418927
Using continuous administration of gonadotropin releasing hormone analogues (GnRH-analogue) to induce a hypoestrogenic state and amenorrhea, leading to uterine fibroid volume reduction, has been reported to be successful and acceptable. Only a few adverse effects related to the therapy have been reported. We report a case of acute onset of abdominal pain, increased sedimentation rate and low grade fever during treatment with intranasal administration of Buserelin acetate. An emergent myomectomy was performed to remove an infarcted intramural myoma. We propose that acute ischemia of a large leiomyoma, especially during the postpartum period, is a noticeable complication during medical treatment with buserelin acetate for uterine leiomyoma.