The role of eosinophil in nasal allergy
Yoshimi, R.
Nihon Rinsho. Japanese Journal of Clinical Medicine 51(3): 820-824
1993
ISSN/ISBN: 0047-1852 PMID: 8492464 Document Number: 416743
In this paper, the function of the eosinophil, activation of the eosinophil and degranulation of eosinophil granules are discussed. The in vitro mechanism of eosinophil-induced tissue injury has been reported previously. We have reported that most of the eosinophils in the inferior turbinate mucous membrane of nasal allergy were positive to EG2 and have also reported that extracellular deposits of EG2, MBP and EPO were mainly found in the superficial lamina propria. However, damage of the epithelia did not relate to the infiltration of EG2, MBP and EPO. The damage of the basement membrane could not be found. The concept of tissue injury induced by eosinophil, is controversial, and further study is required to elucidate the function of the eosinophil, in vivo.