Malnutrition, injury, and the host immune response: nutrient substitution
Gallagher, H.J.; Daly, J.M.
Current Opinion in General Surgery 1993: 92-104
1993
ISSN/ISBN: 1065-6243 PMID: 7584022 Document Number: 416256
Improvements in surgical management and intensive care therapy have enabled many patients to initially survive severe life-threatening trauma or major surgical procedures only to die after delayed bouts of sepsis. This paper reviews literature published within the past year on the effects of nutrient substitution on malnutrition, injury, and the host immune response. Topics discussed include immunodeficiencies in trauma and malnutrition, immunomodulation by nutrition, and parenteral versus enteral nutrition. We also discuss the roles of arginine, glutamine, omega-3 fatty acids, and dietary nucleotides in the host immune response.