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Investigations on Dieffenbachia amoena Gentil. I: Endocrine effects and contraceptive activity

Costa de Pasquale, R.; Ragusa, S.; Circosta, C.; Forestieri, A.M.

Journal of Ethnopharmacology 12(3): 293-303

1984

ISSN/ISBN: 0378-8741
PMID: 6442750
DOI: 10.1016/0378-8741(84)90059-x
Document Number: 415871
Contraceptive activity and the correlated endocrine alterations of an aqueous extract of the leaves of Dieffenbachia amoena were investigated. In female Wistar rats the extract, given for 4 days during the estrous cycle, induced significant variations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL) progesterone and 17 beta-estradiol levels. It also determined a reversible interruption of the estrous cycle with consequent temporary inhibition of ovulation.

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