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Change in the permeability of cardiomyocyte sarcolemma after short-term total ischemia

Eskunov, P.N.

Biulleten' Eksperimental'noi Biologii i Meditsiny 115(1): 80-82

1993

ISSN/ISBN: 0365-9615
PMID: 8054591
Document Number: 415847
Total ischemia (10 min) was produced in experimental rats by compression of the vascular band at the heart base. Sarcolemma permeability was studied with electron-microscopic tracer lantan at the height of ischemia and during 24 hours after resuscitation. It was established that reperfusion induces derangement of glycocalix and elevation of permeability of sarcolemma basal membrane. Plasmatic membrane in most cardiomyocytes was intact. This is an important factor of reversibility of myocardial lesion reperfusion.

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