Severe flare-up in a prostate cancer patient treated with luteinizing hormone-releasing hormone analogue depot
Shimizu, T.; Shibata, Y.; Uchida, T.; Satoh, J.
Hinyokika Kiyo. Acta Urologica Japonica 39(10): 953-955
1993
ISSN/ISBN: 0018-1994 PMID: 8266863 Document Number: 415794
A 65-year-old man with advanced prostate cancer was treated with a luteinizing hormone-releasing hormone (LH-RH) analogue. Four days after the initial injection of 3.6 mg of goserelin acetate, severe dyspnea developed due to worsening pleuritis carcinomatosa, which was considered as a flare-up. Chest drainage was required to save his life. Therefore, we emphasize the importance of treatment to prevent tumor flare during LH-RH analogue therapy.
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