Patterns of proliferation and differentiation of adult myoblasts define a unique myogenic population

Yablonka-Reuveni, Z.

Progress in Clinical and Biological Research 383b: 575-585

1993


ISSN/ISBN: 0361-7742
PMID: 8115374
Document Number: 415571
In here we summarize some of our recent studies on adult chicken myoblasts. We discuss a) myosin isoform expression by the differentiated myoblasts, and b) the role of PDGF during proliferation of the cells. These studies demonstrate that adult myoblasts represent a unique myogenic population (or lineage) which emerges in late development. Furthermore, we discuss possible lineal relationship between adult and somitic/limb bud cells. Unless otherwise noted, the source of myoblasts was chicken pectoralis muscle, and all procedures and antibodies were as described in previous publications (Yablonka-Reuveni, et al., 1987; Yablonka-Reuveni and Seifert, submitted; Hartley, et al., 1991; 1992).

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