A retrospective analysis of the efficacy of the heparin therapy of glomerulonephritis patients
Pyrih, L.A.; Lapchyns'ka, I.I.; Dorets'kyĭ, V.V.
Likars'ka Sprava 1993(7): 84-88
1993
ISSN/ISBN: 1019-5297 PMID: 8209544 Document Number: 415040
Retrospective analysis of heparin efficacy (25,000 IU daily for 3 weeks) was carried out in 59 patients with different morphological and clinical forms of glomerulonephritis. The treatment proved to be effective in 32.2% of patients. Among unsuccessfully treated patients those with severe clinical and morphological forms prevailed. Indication for administration of heparin were specified. Disappearance of fibrin/fibrinogen degradation products from urine or fall in their level by 50% or more a week after the start of heparin were considered prognostically favourable. Graphical turbidimetry is recognized to be the best method of haemostasis monitoring during heparin therapy.