Emerging antiepileptic drugs
Fisher, R.S.
Neurology 43(11 Suppl. 5): S12-S20
1993
ISSN/ISBN: 0028-3878 PMID: 8232982 Document Number: 414306
The introduction of several new antiepileptic drugs in the United States is likely in 1993. Many new drugs have undergone testing, but the four currently considered the most important are felbamate, gabapentin, lamotrigine, and vigabatrin. When these drugs are used as add-on therapy for patients with intractable epilepsy, 20 to 60% of patients show at least a 50% improvement in seizure frequency and 7% become seizure free. An overview of these agents is presented.