Structural similarity of the active sites of major histocompatibility complex class i proteins and ubiquitin

Chipens, G.I.; Inkina, N.M.

Ukrainskii Biokhimicheskii Zhurnal 65(4): 3-7

1993


ISSN/ISBN: 0201-8470
PMID: 8284815
Document Number: 412902
With the help of a new method of protein primary structures analysis, i.e. CAACRA (comparative amino acid codon root analysis) a marked structural similarity of the MHC class I protein active sites and ubiquitin alpha-helix has been revealed. Using the CAACRA a periodicity of ubiquitin primary structure has been shown. Ubiquitin molecule consists of 4 repeat units.

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