A comparative evaluation of the effect of glurenorm and sulfonylurea preparations on the intravascular microcirculatory indices in type-Ii diabetes mellitus
Kakhnovskiĭ, I.M.; Koroleva, T.V.; Zakharchenko, V.N.; Larionov, S.N.
Problemy Endokrinologii 39(2): 7-9
1993
ISSN/ISBN: 0375-9660 PMID: 8016059 Document Number: 412070
Analysis of the effects of glurenorm and some sulfonylurea drugs, such as maninil, minidiab, chlorpropamide, on some parameters of intravascular microcirculation has demonstrated the specific features of this drug. Though all these hypoglycemic agents favorably influence the microcirculation when carbohydrate metabolism compensation is attained, glurenorm improved the status of formed elements of the blood (red cell and platelet aggregation) more noticeably than the rest drugs, which fact recommends it as a drug of choice for patients with type II medium-severe diabetes with the predominant involvement of the cellular component of the microcirculation.