Late ventricular potentials in patients with dilated cardiomyopathy. Correlations with spontaneous ventricular tachycardia and clinical course
Marconi, P.; Ciaccheri, M.; Castelli, G.; Nannini, M.; Arcangeli, C.; Dolara, A.
Giornale Italiano di Cardiologia 23(10): 979-983
1993
ISSN/ISBN: 0046-5968 PMID: 8174865 Document Number: 411586
In a series of 55 patients with dilated cardiomyopathy, the presence of noninvasive recordings of late ventricular potentials (LVP) was correlated to ventricular tachycardia (VT), as detected by a 24-hour Holter monitoring obtained one week within LVP recording. LVPs were found in 12/55 patients (21.8%) and in 2 of a series of 66 normal subjects of the same age and sex. In all patients with LVP either non sustained (11 cases) or sustained (1 case) VT was present at Holter monitoring. In the other 43 patients without LVP only 13 (30%) had non sustained VT (p < 0.01). During the follow-up period (mean 17 months) six patients died suddenly; three of them had LVP and VT (sustained in one); two had non sustained VT, but no LVP; one had neither. This study suggests that the presence of LVP predicts VT recording in ambulatory ECGs. On the contrary, VT may be recorded in patients without LVP. Further studies are necessary to ascertain the value of LVP as a marker of sudden death in patients with dilated cardiomyopathy.