Identification of human DNA in complex biological samples using the Alu polymerase chain reaction
Tsongalis, G.J.; Coleman, W.B.; Esch, G.L.; Smith, G.J.; Kaufman, D.G.
Journal of Forensic Sciences 38(4): 961-967
1993
ISSN/ISBN: 0022-1198 PMID: 8355011 Document Number: 410406
Alu-Polymerase chain reaction (PCR) was used to amplify human DNA from complex mixed sources of DNA. Amplification of human DNA sequences by Alu-PCR could be accomplished in samples containing low concentrations of template in the presence of excess heterologous DNA sequences. Thus, sensitivity and specificity are maintained in complex DNA mixtures allowing positive identification of the presence of human DNA sequences by this technique.
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