Drug sensitivity of bacillus strains M. avium-intracellulare (MAIC) , M. kansasii cultured from patients with mycobacteriosis before treatment
Zwolska-Kwiek, Z.; Augustynowicz-Kopeć, E.; Zalewska-Schöntaler, N.
Pneumonologia i Alergologia Polska 61(5-6): 248-253
1993
ISSN/ISBN: 0867-7077 PMID: 8348088 Document Number: 410053
The aim of study was to evaluate a drug sensitivity of M. avium-intracellulare, M. xenopi and M. kansasii cultured from 55 patients with mycobacterioses. The identification of strains was performed with morphological and biochemical tests and thin-layer chromatography. Resistance tests were done on egg L-J and agar media for selected drugs. It was documented that MAIC strains were non-sensitive on isoniazid and rifampicin, and other ones. The most active drug was cycloserine inhibiting growth of 80% but rifabutine--50% of strains. M. xenopi strains were sensitive for tested drugs including isoniazid and rifampicin (about 30%). M. kansasii strains were in 100% sensitive for cyclosporine, rifabutine, Davercin and ofloxacin and partly for isoniazid, streptomycin and Augmentin.