Synthesis of platelet activation factor analogs
Sablina, M.A.; Ushakova, I.P.; Dement'eva, E.V.; Dergousov, A.A.; Serebrennikova, G.A.
Bioorganicheskaia Khimiia 19(3): 354-359
1993
ISSN/ISBN: 0132-3423 PMID: 8489534 Document Number: 409680
Novel structural analogues of the platelet activating factor (PAF), rac-1-octadecyl-2-allyl-glycerol-3-phosphocholine and rac-1-octadecyl-2-allyl-1-thioglycerol-3-phosphocholine , have been synthesized. The phospholipids obtained showed neither PAF-agonistic nor PAF-antagonistic activity at the concentration of 10(-5) to 10(-7) M.
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