The efficacy of phloridzin and phloretin on tumor cell growth
Nelson, J.A.; Falk, R.E.
Anticancer Research 13(6a): 2287-2292
1993
ISSN/ISBN: 0250-7005 PMID: 8297148 Document Number: 409639
This study utilized phloridzin (P1) and its aglucone phloretin (P2), two known inhibitors of glucose transmembrane transport, to inhibit tumor cell growth in vivo. The efficacy of hydrazine sulfate as an anticachexic agent was also evaluated. Utilizing the rat mammary adenocarcinoma and Fischer bladder cell carcinoma cell lines, it has been shown that the i.p. administration of P1 and P2 can produce significant differences in mean tumor diameters as compared to the untreated controls.
Document emailed within 1 workday
Related Documents
Ohnishi, K.; Bonavida, B. 1987: Regulation of Ia+ reticulum cell sarcoma (RCS) growth in syngeneic SJL/J mice. I. Inhibition of tumor growth by passive administration of L3T4 monoclonal antibody before or after tumor inoculation Journal of Immunology 138(12): 4524-4529Suzuki, Y.; Chen, L.P.; Liu, C.M.; Morita, T.; Wheelock, E.F. 1989: Immune regulation of the L5178Y murine tumor-dormant state: induction of cell- and soluble factor-mediated inhibition of tumor cell growth by tumor necrosis factor and gamma-interferon Cancer Research 49(8): 2028-2033
Rueda, F.; Piñol, G.; Gonzalez-Garrigues, M.; Marti, F.; Fabra, A. 1989: Transforming growth factor release by human tumor cell lines and their interactions with other growth factors Anticancer Research 9(4): 1245-1248
Buck, C.; Digel, W.; Schöniger, W.; Stefanic, M.; Ragnavachar, A.; Heimpel, H.; Porzsolt, F. 1990: Tumor necrosis factor-alpha, but not lymphotoxin, stimulates growth of tumor cells in hairy cell leukemia Leukemia 4(6): 431-434
Hermens, A.F. 2004: Increased tumor growth of non-small-cell lung tumor in the waiting time between induction chemotherapy and longterm radiotherapy Nederlands Tijdschrift Voor Geneeskunde 148(46): 2300
Fisher, B.; Gunduz, N. 1979: Further observations on the inhibition of tumor growth by Corynebacterium parvum with cyclophosphamide. X. Effect of treatment on tumor cell kinetics in mice Journal of the National Cancer Institute 62(6): 1545-1551
Yoysungnoen, B.; Bhattarakosol, O.; Changtam, C.; Patumraj, S. 2016: Combinational Treatment Effect of Tetrahydrocurcumin and Celecoxib on Cervical Cancer Cell-Induced Tumor Growth and Tumor Angiogenesis in Nude Mice Journal of the Medical Association of Thailand 99 Suppl. 4: S23-S31
Sandru, G.; Veraguth, P.; Stadler, B.M. 1988: Stimulation of tumor cell growth in humans by a mononuclear cell-derived factor Cancer Research 48(19): 5411-5416
Fryling, C.M.; Iwata, K.K.; Johnson, P.A.; Knott, W.B.; Todaro, G.J. 1985: Two distinct tumor cell growth-inhibiting factors from a human rhabdomyosarcoma cell line Cancer Research 45(6): 2695-2699
Norbury, K.C. 1977: In vitro stimulation and inhibition of tumor cell growth mediated by different lymphoid cell populations Cancer Research 37(5): 1408-1415
Iwata, K.K.; Fryling, C.M.; Knott, W.B.; Todaro, G.J. 1985: Isolation of tumor cell growth-inhibiting factors from a human rhabdomyosarcoma cell line Cancer Research 45(6): 2689-2694
Joly-Pharaboz, M.O.; Fei, Z.L.; Bouillard, B.; Andre, J. 1990: Estradiol stimulation and inhibition of cell growth in new estrogen-sensitive cell lines and tumors established from the MtTF4 tumor Cancer Research 50(12): 3786-3794
Stukov, A.N.; Ivanova, M.A.; Nikitin, A.K.; Sorokin, G.M.; Kon'kov, S.A. 2001: Tumor growth index as an integral criterion for the efficacy of antineoplastic therapy under experimental conditions Voprosy Onkologii 47(5): 616-618
Yagita, H.; Masuko, T.; Hashimoto, Y. 1986: Inhibition of tumor cell growth in vitro by murine monoclonal antibodies that recognize a proliferation-associated cell surface antigen system in rats and humans Cancer Research 46(3): 1478-1484
Itashiki, Y.; Harada, K.; Ferdous, T.; Yoshida, H. 2007: Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with fluoropyrimidine anticancer agent, S-1, on tumor growth of human oral squamous cell carcinoma xenografts in nude mice Anticancer Research 27(4b): 2365-2375
Cosić, S.J.; Kovac, Z. 2011: Clinical and etiopathogenetic role of plasminogen and metaloproteinase systems in the tumor growth. Pericellular proteolysis of extracellular matrix and tumor growth Lijecnicki Vjesnik 133(1-2): 56-63
Pedrazzoli, P.; Gibelli, N.; Poggi, G.; Zambelli, A.; Saverio, F.; Della Cuna, R.; Locatelli, F.; Zibera, C. 1995: Stem cell factor and interleukin-6, alone or in combination with granulocyte colony-stimulating factor, do not affect the growth of solid tumor cell lines Anticancer Research 15(1): 25-28
Radinsky, R.; Fidler, I.J. 1992: Regulation of tumor cell growth at organ-specific metastases In Vivo 6(4): 325-331
Lenhard, V.; Scholler, P.; Zeller, W. 1989: Transfusion-induced T suppressor cell activity and experimental tumor growth Transplantation Proceedings 21(1 Part 1): 580-583
Goto, M.; Kataoka, Y.; Goto, K.; Yokoyama, T.; Sato, H. 1972: Decrease in agglutinability of cultured tumor cells to concanavalin-A at the plateau of cell growth Gan 63(4): 505-506