HIV-1 seropositivity in pulmonary tuberculosis (study of 340 cases from Marathwada)
Talib, S.H.; Bansal, M.P.; Kamble, M.M.
Indian Journal of Pathology and Microbiology 36(4): 383-388
1993
ISSN/ISBN: 0377-4929 PMID: 8157305 Document Number: 408947
In Marathwada region of Maharashtra State, India, clinicians obtained blood samples from 340 pulmonary and presumed pleural tuberculosis (TB) patients at the TB Wing of the Government Medical College Hospital in Aurangabad to determine the HIV seropositivity rate of the cases. All samples testing positive for an ELISA would undergo another ELISA to confirm the first ELISA's results. The ELISA commercial kits were Serodia and Vironostika. 16 cases tested positive for HIV by both ELISA tests. The sexual preference of all 16 cases was heterosexual. Males and 20-39 year olds were the predominant groups (12 vs. 4 for both groups). No case was younger than 20 years old. Six HIV-positive male TB patients had had multiple partners. Three of them also had genital ulcer disease, a cofactor facilitating HIV transmission. Six HIV-positive TB patients had a history of receiving streptomycin injections and 2 of them had also had multiple partners. 25% of HIV-positive TB patients had pleural effusion. 12 cases had TB clinical features (lower zone infiltration, hilar/mediastinal adenopathy, and diffuse infiltration without cavitation) associated with greater impairment of cell mediated immunity.