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Role of mechanical ventilation in acute severe asthma

Batra, Y.K.; Sarnaik, R.M.; Gupta, S.; Jindal, S.K.

Indian Journal of Chest Diseases and Allied Sciences 35(4): 179-183

1993

ISSN/ISBN: 0377-9343
PMID: 8039818
Document Number: 408823
During the last 4 years, fifty-seven patients of acute severe asthma (ASA) were admitted to intensive care unit (ICU). Twenty-three patients required mechanical ventilation (MV) on 25 occasions. Indications to intubate were persistent hypoxia (PaO2 < or = 55 mm Hg) or hypercapnia with respiratory acidosis (64%), abnormal mentation (24%) and respiratory arrest (12%). All the patients were monitored for clinical features, arterial blood gases (ABG) and peak airway pressure (PAP). During MV, there was one case of pneumothorax (4%), seven (28%) cases of transient hypertension and one (4%) patient died. Mean duration of MV was 3 days and the outcome was favourable. Therefore, resorting to aggressive treatment early in the course of disease proves life saving in acute severe asthma.

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