A biochemical study of creatine phosphokinase in the myocardium and its morphological changes in patients with acute vascular surgical pathology
Trusov, O.A.; Avilov, V.V.; Mozhina, A.A.; Tsareva, L.A.
Kardiologiia 33(10): 41
1993
ISSN/ISBN: 0022-9040 PMID: 8139171 Document Number: 406205
The structure and metabolism of various myocardial portions, including the activity of creatine phosphokinase (CPK), were studied by using the autopsies of patients who had died in a surgical clinic. The biochemical studies demonstrated a decrease in CPK activity, which was pronounced in patients with atherosclerotic aneurysm and abdominal aortic rupture. The morphological studies revealed individual cardiomyocytic lesions, segmental lesions of papillary muscle. There was reduced activity of redox enzymes in the fragmentation areas of muscle fibers. Various surgical abnormality of vessels was accompanied by progressive myocardial hypoxia and drastically decreased activity of CPK and the tested hydroxyreductases.