Pathology of muscle contracture caused by injection and activity of phosphochesterase and insulin receptor
Liu, M.; Peng, M.; Hu, T.; Chen, M.; Lang, S.
Hua Xi Yi Ke da Xue Xue Bao 24(3): 278-280
1993
ISSN/ISBN: 0257-7712 PMID: 8288197 Document Number: 405653
The animal model of muscle contracture caused by injection was set up in the experiment. We used the model for excessive healing studies and researched the changes in its pathology, and activity of phosphochesterase and insulin receptor in this model. The experimental results revealed that the pathologic changes belonged to excessive proliferation of connective tissue (excessive healing). When occurred muscle degeneration, infiltration of inflammatory cells, proliferation of fibroblasts and descending of collagen fibers, the activity level phosphochesterase and insulin receptor became higher. The excessive healing occurrence may have something to do with the changes of phosphochesterase and insulin receptor.