Tetrazepam in the treatment of acute cervical syndrome. Randomized double-blind pilot study comparing tetrazepam and placebo

Salzmann, E.; Wiedemann, O.; Löffler, L.; Sperber, H.

Fortschritte der Medizin 111(34): 544-548

1993


ISSN/ISBN: 0015-8178
PMID: 8307542
Document Number: 405225
In a double-blind study, 20 ambulatory patients with acute painful restriction of mobility of the cervical spine and overall marked impairment were treated for seven days with tetrazepam (150 mg or a lower dose from the third day onward) or placebo. Paracetamol was permitted in addition if required. Test criteria: The main criterion of efficacy was a summed score of three parameters: pain, restriction of mobility, and general impairment. The difference between the groups was statistically highly significant (p = 0.005). Tolerability was adjudged to be "very good" for the placebo group, and, on average, "good" for the tetrazepam group.

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