Trisomy 18 (Edwards syndrome) : two case reports
Morosini, P.; Verdura, C.; Paolillo, F.; Fornari, M.; Argentiero, M.L.; Belloni, C.
La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 14(1): 75-77
1992
ISSN/ISBN: 0391-5387 PMID: 1579521 Document Number: 404689
Edwards (or trisomy 18) syndrome, with a frequency of about 1 over 8000 births, is commonly characterized by a very short survival; those rare cases reported with ages of 12 months or more, always were demonstrated to be chromosomic mosaicisms. Two affected children with completely different outcomes are here described; the first with a classic short-life evolution, in opposition to the second with long survival, the last a good example of all those various biological, psychological and social support interventions in these circumstances, very rare to match with, for this appears to be a trisomy 18 without mosaicism.