The use of thyrotropin-releasing hormone in clinical practice as a lymphatic stimulator in the treatment of acute pancreatitis
Shimanko, I.I.; Limarev, V.M.; Ashmarin, I.P.; Lelekova, T.V.; Sanzhieva, L.T.
Khirurgiia 1: 64-66
1992
ISSN/ISBN: 0023-1207 PMID: 1578846 Document Number: 404308
Experiments were conducted to study the modulating effect of thyrotropin-releasing hormone, (TRH) on the contractility of lymphatic vessels of the rat mesenterium. Later, TRH was applied in the clinic in the treatment of edematous and destructive forms of acute pancreatitis in 15 patients. as a result, echoscopy showed diminished edema of the pancreas, amylasemia decreased, the concentration of middle mass molecules in the blood reduced and their transport in the urine intensified. The agent was infused into the veins and into the lymphatic vessels, which allowed its dose to be reduced by half.